This posting is the fifth and final part of the TI Deaths of Despair series. The series explores whether and to what extent Deaths of Despair, caused by behaviors such as heavy drinking, drug use and suicide, are affecting Texas. These deaths have been observed on a national level in studies by Deaton-Case who have identified a flattening out and, in some case, growth in mortality rates among some White middle-aged Americans, while the century-long decline in mortality rates continues for other races and ethnicities of the same age. Deaton and Case link the behaviors resulting in Deaths of Despair to cumulative disadvantages experienced in the labor market by White Non-Hispanic middle-aged persons without college degrees. This posting explores the behaviors allegedly causing such deaths in Texas and attempts to verify whether or not these deaths are increasing disproportionately among White middle-aged Texans.